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National Institute for Applied Statistics Research Australia Seminar Series
January 14 @ 2:00 pm - 3:00 pm
Associate Professor Robin Turner
University of Otago
Designing randomised trials to estimate the benefits and harms of patient choice of treatment
With the increased use of shared decision making, it is increasingly important to provide evidence on the impact that patient treatment choice has on outcomes. Two-stage randomised trials, incorporating participant choice, offer the opportunity to determine the effects of choice, which is not estimable in standard trials. In order to answer important questions about the effect of choice, these trials need to be adequately powered. This talk will cover the design issues for this type of trial and the situations in which this design may be most beneficial.